Journal Title (Medline/Pubmed accepted abbreviation): Int. J. Sport Nutr. Exerc. Metabol.
Page numbers: 393-400
doi (if applicable):
Background:It is common practice for athletes to ingest high doses of fast-absorbing carbohydrate (ex. maltodextrin) either during training (carb loading) or after a workout to regenerate glycogen stores. However, it has been shown that carbohydrate-rich meals, due to their large increases in postprandial glycemia, may lead to the formation of potentially harmful reactive oxygen and nitrogen species (RONS) in different tissues (e.g., vascular endothelial cells).
Hypothesis/purpose of study:The authors hypothesized that meals of either dextrose or maltodextrin would increase markers of oxidative stress, with greater responses observed for dextrose versus maltodextrin.
Subjects:10 healthy, male, nonsmokers, age 27 ± 7 yrs, BMI 25 ± 4 kg/m2
Treatments and protocol:
Participants completed food diaries for the 6 days prior to laboratory testing.
Participants arrived at the laboratory after an overnight fast. A baseline venous blood sample was collected and then participants consumed 2.25 g/kg body weight of either dextrose or maltodextrin (182.25 ± 42.75 g, 729 ± 171 kcal) in an aqueous solution (~730 kcal per participant). Additional blood samples were acquired at 1, 2, 4, and 6 hrs after carbohydrate consumption. Markers of oxidant stress (e.g., malondialdehyde, hydrogen peroxide, nitrates/nitrites), antioxidant capacity (e.g., Trolox-equivalent antioxidant capacity, or TEAC), and metabolic status (e.g., glucose, triacylglycerol) were measured in the blood samples.