Journal Title (Medline/Pubmed accepted abbreviation): Br J Sports Med
Page numbers: 1077-1078
doi (if applicable):10.1136/bjsports-2011-090460
Article Type: Review(brief)
Summary of article
The authors have written a brief review of melatonin, methylsulphonylmethane (MSM), and melamine. Melatonin is a hormone that has effects on circadian rhythms, sleep onset, and reproductive systems. Athletes may be interested in melatonin supplements to enhance heat loss during exercise and improve recovery from jet lag. There is also a potential association between disruption of normal melatonin production and increased risk of amenorrhea. MSM occurs naturally in certain foods and has been used as a nutritional supplement for osteoarthritis, allergic rhinitis, and autoimmune diseases, and as a throat spray for snoring. Athletes use MSM for muscle soreness, but there is no clinical evidence to support this use. Melamine is used in plastic production and has no ergogenic ability. However, it has a high nitrogen content and has been used illegally to elevate protein quantity in supplements. Melamine is toxic in low doses and especially affects the kidneys.
Interpretation of findings/Key practice applications
There is very little evidence to support the effects of jet lag on exercise performance. However, athletes have reported subjective feelings of improvement from jet lag symptoms with melatonin supplements. Based on limited clinical evidence, MSM cannot be recommended at this time for pain relief from delayed-onset muscle soreness. Finally, all supplement usage should be discussed with a professional nutritionist before adding to a dietary regimen; contamination with toxic substances can occur.